description
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxic T cells, causing infectious mononucleosis during adolescence. Primary infection with EBV is followed by latent infection in which the reservoir B cells are immortalized. EBV tumorigenic potential in Burkitt lymphoma, nasopharyngeal carcinoma, Hodgkin lymphoma, and post-transplant B cell lymphomas has been well-documented. Distinct forms of EBV latency and patterns of latent gene expression can contribute to the different tumours

external resources
NCBI:585562
KEGG:hsa05169
PUBMED:1658397
PUBMED:10683340
PUBMED:19375142
PUBMED:12438576
PUBMED:12910248
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PUBMED:17159145
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PUBMED:18786993
PUBMED:16603506
PUBMED:10644367
PUBMED:15021898
PUBMED:10666279
PUBMED:9565632

genes
AKT1 , AKT2 , BCL2 , POLR3D , CCNA2 , CD19 , CD38 , ENTPD1 , ENTPD3 , CD40 , CD44 , CD58 , CDK1 , CDK2 , CDKN1A , CDKN1B , CHUK , CR2 , ATF2 , CREBBP , MAPK14 , CSNK2A1 , CSNK2A2 , CSNK2B , EP300 , FCER2 , FGR , GSK3B , GTF2B , GTF2E1 , GTF2E2 , HDAC1 , HDAC2 , HLA-A , HLA-B , HLA-C , HLA-DPA1 , HLA-DPB1 , HLA-DQA1 , HLA-DQA2 , HLA-DQB1 , HLA-DRA , HLA-DRB1 , HLA-DRB5 , HLA-E , HLA-F , HLA-G , HSPA1A , HSPA1B , HSPA1L , HSPA2 , HSPA6 , HSPA8 , HSPB1 , HSPB2 , ICAM1 , IFNG , RBPJ , IKBKB , IL10 , IL10RA , IL10RB , IRAK1 , IRF3 , ITGAL , JAK1 , JAK3 , JUN , LYN , MDM2 , MYC , NEDD4 , NFKB1 , NFKB2 , NFKBIA , NFKBIB , NFKBIE , PIK3CA , PIK3CB , PIK3CD , PIK3R1 , PIK3R2 , PLCG1 , PLCG2 , POLR2A , POLR2B , POLR2C , POLR2D , POLR2E , POLR2F , POLR2G , POLR2H , POLR2I , POLR2J , POLR2K , POLR2L , PRKACA , PRKACB , PRKACG , MAPK8 , MAPK11 , MAPK9 , MAPK10 , MAPK13 , MAP2K3 , MAP2K6 , MAP2K7 , EIF2AK2 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD7 , PSMD8 , PSMD11 , PSMD12 , PSMD13 , PTMA , RAN , RB1 , RELA , RELB , MAPK12 , MAP2K4 , SKP2 , SPI1 , SPN , STAT3 , SYK , MAP3K7 , TBP , TNFAIP3 , TP53 , TRAF1 , TRAF2 , TRAF3 , TRAF5 , TRAF6 , TYK2 , VIM , XPO1 , YWHAB , YWHAE , YWHAG , YWHAH , YWHAZ , USP7 , SEM1 , NUP214 , PIK3R3 , IKBKG , TRADD , RIPK1 , CCNA1 , MAP3K14 , EIF2AK3 , TBPL1 , POLR1C , NCOR2 , HDAC4 , PSMD6 , AKT3 , HDAC5 , PSMD14 , TAB1 , POLR3F , POLR3G , POLR3C , YWHAQ , ADRM1 , POLR3A , RBPJL , SNW1 , TAB2 , DDX58 , AKAP8L , SND1 , EIF2AK1 , TBK1 , POLR1D , POLR3K , POLR3B , POLR3E , POLR3GL , POLR3H , POLR2J2 , CSNK2A3 , ENTPD8 , TBPL2 , EIF2AK4 , POLR2J3 ,